Effect of genistein, a tyrosine kinase inhibitor, on TAME-esterase induced contractions in rat aorta in vitro.

نویسندگان

  • F B H Gurib
  • A H Subratty
چکیده

Effect of genistein, a protein tyrosine kinase inhibitor, on TAME-esterase induced contractions were studied on rat aorta strips in vitro. Data showed that TAME-esterase induced contractions were concentration dependent and these contractions were significantly inhibited when rat aorta strips were pre-incubated with genistein. The present findings provide evidence for the possible contribution of tyrosine kinases during TAME-esterase induced contractions in aorta.

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عنوان ژورنال:
  • Indian journal of experimental biology

دوره 40 10  شماره 

صفحات  -

تاریخ انتشار 2002